Host Pathogen Interactions
Objectives / Study Questions:Chapter 15: Microbial Mechanisms of Pathogenicity
Chapter 16: Innate
Immunity, Nonspecific Defenses of the Host
- Identify the principal portals of entry.
- Using examples, explain how microbes adhere to host cells.
- Explain how capsules and cell wall components contribute to pathogenicity.
- Compare the effects of coagulases, kinases, hyaluronidase, and collagenase, and IgA proteases.
- Describe how bacteria use the host cell's cytoplasm to enter the cell.
- Describe the function of siderophores.
- Contrast the nature and effects of exotoxins and endotoxins.
- Classify diphtheria toxin, erythrogenic toxin, botulinum toxin, tetanus toxin, Vibrio enterotoxin, and staphylococcal enterotoxin.
- Using examples, describe the role of plasmids and lysogeny in pathogenicity.
- List nine cytopathic effects of viral infections.
- Discuss the causes of symptoms in fungal, protozoan, helminthic, and algal diseases.
between innate and adaptive immunity.
the role of the skin and mucous membranes in innate immunity.
the role of normal microbiota in innate resistance.
phagocytic cells, and describe the roles of each.
phagocyte and phagocytosis.
the process of phagocytosis, and include the stages of adherence and ingestion.
six methods of avoiding destruction by phagocytes.
the stages of inflammation.
the roles of vasodilation in inflammation.
10. Describe phagocyte migration.
11. Describe the cause and effects of