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Host Pathogen Interactions
Objectives / Study Questions: Chapter 15: Microbial Mechanisms of Pathogenicity
- Identify the principal portals of entry.
- Using examples, explain how microbes adhere to host cells.
- Explain how capsules and cell wall components contribute to pathogenicity.
- Compare the effects of coagulases, kinases, hyaluronidase, and collagenase, and IgA proteases.
- Describe how bacteria use the host cell's cytoplasm to enter the cell.
- Describe the function of siderophores.
- Contrast the nature and effects of exotoxins and endotoxins.
- Classify diphtheria toxin, erythrogenic toxin, botulinum toxin, tetanus toxin, Vibrio enterotoxin, and staphylococcal enterotoxin.
- Using examples, describe the role of plasmids and lysogeny in pathogenicity.
- List nine cytopathic effects of viral infections.
- Discuss the causes of symptoms in fungal, protozoan, helminthic, and algal diseases.
Chapter 16: Innate
Immunity, Nonspecific Defenses of the Host
1. Differentiate
between innate and adaptive immunity.
2. Describe
the role of the skin and mucous membranes in innate immunity.
3. Describe
the role of normal microbiota in innate resistance.
4. Classify
phagocytic cells, and describe the roles of each.
5. Define
phagocyte and phagocytosis.
6. Describe
the process of phagocytosis, and include the stages of adherence and ingestion.
7. Identify
six methods of avoiding destruction by phagocytes.
8. List
the stages of inflammation.
9. Describe
the roles of vasodilation in inflammation.
10. Describe phagocyte migration.
11. Describe the cause and effects of
fever.
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